Galea, E. , Weinstock, L., Larramona, R., Pybus, A., Gimenez-Llort, G., Escartin, C., Wood, L. , 2022. Multi-transcriptomic analysis points to early organelle dysfunction in human astrocytes in Alzheimer's disease. Neurobiology of Disease, 166: 105655

​

Misko, A., Weinstock, L., Sankar, S., Furness, A., Grishchuk, Y., Wood, L., 2022. Peripheral inflammatory cytokine signature mirrors motor deficits in mucolipidosis IV. Cells, 11(3): 546. 

​

O'Melia, M., Mulero-Russe, A., Kim, J., Pybus, A., DeRyckere, D., Wood, L., Graham, D., Botchwey, E., García, A., Thomas, S., 2022. Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening. Advanced Materials, e2108084. doi: 10.1002/adma.202108084.

​

McKinney, J., Pucha, K., Doan, T., Wang, L., Weinstock, L., Tignor, B., Fowle, K., Levit, R., Wood, L., Willett, N., 2022. Sodium alginate microencapsulation of human mesenchymal stromal cells modulates paracrine signaling response and enhances efficacy for treatment of established osteoarthritis. Acta Biomaterialia, 141(15): 315-332.

​

He, Q., Colon-Motas, K., Pybus, A., Piendel, L., Seppa, J., Walker, M., Manzanares, C., Qiu, D., Miocinovic, S., Wood, L., Levey, A., Lah, J., Singer, A., 2021. A feasibility trial of gamma sensory flicker for patients with prodromal Alzheimer's disease. Alzheimer’s and Dementia, 7(1): e12178.

 

Misko, A.; Wood, L.; Kiselyov, K.; Slaugenhaupt, S.; Grishchuk, Y. Progress in Elucidating Pathophysiology of Mucolipidosis IV. Neurosci. Lett. 2021, 755, 135944. 

 

Chen, M. J.; Ramesha, S.; Weinstock, L. D.; Gao, T.; Ping, L.; Xiao, H.; Dammer, E. B.; Duong, D. D.; Levey, A. I.; Lah, J. J.; Seyfried, N. T.; Wood, L. B.; Rangaraju, S. Extracellular Signal-Regulated Kinase Regulates Microglial Immune Responses in Alzheimer’s Disease. J. Neurosci. Res. 2021, 99 (6), 1704–1721. 

 

Amanso, A. M.; Kamalakar, A.; Bitarafan, S.; Abramowicz, S.; Drissi, H.; Barnett, J. V.; Wood, L. B.; Goudy, S. L. Osteoinductive Effect of Soluble Transforming Growth Factor Beta Receptor 3 on Human Osteoblast Lineage. J. Cell. Biochem. 2021, 122 (5), 538–548.

 

Ramesha, S.; Rayaprolu, S.; Bowen, C. A.; Giver, C. R.; Bitarafan, S.; Nguyen, H. M.; Gao, T.; Chen, M. J.; Nwabueze, N.; Dammer, E. B.; Engstrom, A. K.; Xiao, H.; Pennati, A.; Seyfried, N. T.; Katz, D. J.; Galipeau, J.; Wulff, H.; Waller, E. K.; Wood, L. B.; Levey, A. I.; Rangaraju, S. Unique Molecular Characteristics and Microglial Origin of Kv1.3 Channel–Positive Brain Myeloid Cells in Alzheimer’s Disease. Proc. Natl. Acad. Sci. 2021, 118 (11). 

​

Escartin, C.; Galea, E.; Lakatos, A.; O’Callaghan, J. P.; Petzold, G. C.; Serrano-Pozo, A.; Steinhäuser, C.; Volterra, A.; Carmignoto, G.; Agarwal, A.; Allen, N. J.; Araque, A.; Barbeito, L.; Barzilai, A.; Bergles, D. E.; Bonvento, G.; Butt, A. M.; Chen, W.-T.; Cohen-Salmon, M.; Cunningham, C.; Deneen, B.; De Strooper, B.; Díaz-Castro, B.; Farina, C.; Freeman, M.; Gallo, V.; Goldman, J. E.; Goldman, S. A.; Götz, M.; Gutiérrez, A.; Haydon, P. G.; Heiland, D. H.; Hol, E. M.; Holt, M. G.; Iino, M.; Kastanenka, K. V.; Kettenmann, H.; Khakh, B. S.; Koizumi, S.; Lee, C. J.; Liddelow, S. A.; MacVicar, B. A.; Magistretti, P.; Messing, A.; Mishra, A.; Molofsky, A. V.; Murai, K. K.; Norris, C. M.; Okada, S.; Oliet, S. H. R.; Oliveira, J. F.; Panatier, A.; Parpura, V.; Pekna, M.; Pekny, M.; Pellerin, L.; Perea, G.; Pérez-Nievas, B. G.; Pfrieger, F. W.; Poskanzer, K. E.; Quintana, F. J.; Ransohoff, R. M.; Riquelme-Perez, M.; Robel, S.; Rose, C. R.; Rothstein, J. D.; Rouach, N.; Rowitch, D. H.; Semyanov, A.; Sirko, S.; Sontheimer, H.; Swanson, R. A.; Vitorica, J.; Wanner, I.-B.; Wood, L. B.; Wu, J.; Zheng, B.; Zimmer, E. R.; Zorec, R.; Sofroniew, M. V.; Verkhratsky, A. Reactive Astrocyte Nomenclature, Definitions, and Future Directions. Nat. Neurosci. 2021, 24 (3), 312–325. 

​

Cheng, A.; Vantucci, C. E.; Krishnan, L.; Ruehle, M. A.; Kotanchek, T.; Wood, L. B.; Roy, K.; Guldberg, R. E. Early Systemic Immune Biomarkers Predict Bone Regeneration after Trauma. Proc. Natl. Acad. Sci. 2021, 118 (8). 

 

Kamalakar, A.; McKinney, J. M.; Salinas Duron, D.; Amanso, A. M.; Ballestas, S. A.; Drissi, H.; Willett, N. J.; Bhattaram, P.; García, A. J.; Wood, L. B.; Goudy, S. L. JAGGED1 Stimulates Cranial Neural Crest Cell Osteoblast Commitment Pathways and Bone Regeneration Independent of Canonical NOTCH Signaling. Bone 2021, 143, 115657. 

​

Klosterhoff, B. S.; Vantucci, C. E.; Kaiser, J.; Ong, K. G.; Wood, L. B.; Weiss, J. A.; Guldberg, R. E.; Willett, N. J. Effects of Osteogenic Ambulatory Mechanical Stimulation on Early Stages of BMP-2 Mediated Bone Repair. Connect. Tissue Res. 2021, 0 (0), 1–12. 

​

Vantucci, C. E.; Ahn, H.; Fulton, T.; Schenker, M. L.; Pradhan, P.; Wood, L. B.; Guldberg, R. E.; Roy, K.; Willett, N. J. Development of Systemic Immune Dysregulation in a Rat Trauma Model of Biomaterial-Associated Infection. Biomaterials 2021, 264, 120405. 

​

Ruehle, M. A.; Eastburn, E. A.; LaBelle, S. A.; Krishnan, L.; Weiss, J. A.; Boerckel, J. D.; Wood, L. B.; Guldberg, R. E.; Willett, N. J. Extracellular Matrix Compression Temporally Regulates Microvascular Angiogenesis. Sci. Adv. 2020, 6 (34), eabb6351. 

​

Weinstock, L. D.; Forsmo, J. E.; Wilkinson, A.; Ueda, J.; Wood, L. B. Experimental Control of Macrophage Pro-Inflammatory Dynamics Using Predictive Models. Front. Bioeng. Biotechnol. 2020, 8, 666. 

​

Rayaprolu, S., Gao, T., Xiao, H., Ramesha, S., Weinstock, L. D., Shah, J., Duong, D. M., Dammer, E. B., Webster, J. A., Lah, J. J., Wood, L. B., Betarbet, R., Levey, A. I., Seyfried, N. T., Rangaraju, S., 2020. "Flow-Cytometric Microglial Sorting Coupled with Quantitative Proteomics Identifies Moesin as a Highly-Abundant Microglial Protein with Relevance to Alzheimer’s Disease", Molecular Neurodegeneration,15(1):28.

​

Sankar, S.B., Infante-Garcia, C., Weinstock, L.D., Ramos-Rodriguez, J.J., Hierro-Bujalance, C., Fernandez-Ponce, C., Wood, L.B.†, Garcia-Alloza, M.†, 2020. "Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer’s mouse model", Journal of Neuroinflammation,17(1):38. †Equally contributing senior authors.

​

Garza, K.M., Zhang, L., Borron, B., Wood, L.B., Singer, A.C., 2020. "Gamma Visual Stimulation Induces a Neuroimmune Signaling Profile Distinct from Acute Neuroinflammation", Journal of Neuroscience, 40:1211–1225.

​

Earls, R.H., Menees, K.B., Chung, J., Gutekunst, C.-A., Lee, H.J., Hazim, M.G., Rada, B., Wood, L.B., Lee, J.-K., 2020. "NK cells clear α-synuclein and the depletion of NK cells exacerbates synuclein pathology in a mouse model of α-synucleinopathy", Proceedings of the National Academy of Science, 117:1762–1771.

​

Sankar, S.B.*, Pybus, A.F.*, Liew A., Sanders, B., Shah, K.J., Wood, L.B.†, Buckley E.M.†, 2019. "Low cerebral blood flow is a non-invasive biomarker of neuroinflammation after repetitive mild traumatic brain injury", Neurobiology of Disease, 124: 544-554. *Equally contributing first and second authors, †Equally contributing senior authors.

​

Cheng, A., Krishnan, L., Pradhan, P., Weinstock, L.D., Wood, L.B., Roy, K., Guldberg, R.E., 2019. "Impaired bone healing following treatment of established nonunion correlates with serum cytokine expression", Journal of Orthopaedic Research, 37(2): 299-307.

​

Barroeta-Espara, I.*, Weinstock, L.D.*, Perez-Nievas, B.G., Meltzer, A.C., Siao Tick Chong, M, Amaral, A.C., Murray, M.E., Moulder, K.L., Morris, J.C., Cairns, N.J., Parisi, J.E., Lowe, V.J., Petersen, R.C., Kofler J., Ikonomovic M.D., López, O. Klunk, W.E., Mayeux, R.P., Frosch, M.P., Wood, L.B.†, Gomez-Isla, T†., 2019. "Distinct cytokine profiles in human brains resilient to Alzheimer's pathology", Neurobiology of Disease, 121: 327-337.

*Equally contributing first and second authors, †Equally contributing senior authors.

​

Sankar, S.*, Donegan, R.*, Shah, K.J., Reddi, A.†, Wood, L.B.†, 2018. "Heme and hemoglobin suppress amyloid β–mediated inflammatory activation of mouse astrocytes", J. Biol. Chem., 293(29):11358-11373. *Equally contributing first and second authors, †Equally contributing senior authors.

​

Weinstock, L., Furness, A., Herron, S., Smith, S., Sankar, S.B., DeRosa, S., Gao, D., Mepyans, M., Rosato, A., Medina, D., Vardi, A., Ferreira, N., Cho, S., Futerman, A., Slaugenhaupt, S., Wood, L.B.†, Grishchuk, Y.†, 2018. "Fingolimod Phosphate Modulates Astrocyte Inflammatory Activity in Mucolipidosis IV", Human Mol. Gen., 27(15):2725–2738.†Equally contributing senior authors. Cover Article.

​​

​Caroti, C.M., Ahn, H., Salazar, H.F., Joseph, G., Sankar, S.B., Willett, N.J., Wood, L.B., Taylor W.R., Lyle A.N., 2017. "A Novel Technique for Accelerated Culture of Murine Mesenchymal Stem Cells that Allows for Sustained Multipotency" Scientific Reports, 7. doi:10.1038/s41598-017-13477-y.

​​

Gierut, J.*, Wood, L.B.*, Lau, K., Lin, Y., Genetti, C., Samatar, A., Lauffenburger, D., Haigis, K., 2015. “Network-level effects of kinase inhibitors modulate TNF-α induced apoptosis in the intestinal epithelium,” Science Signaling, 8(407): ra129. *Equally contributing first and second authors.

​

Wood, L.B., Winslow, A., Proctor, E., McGuone, D., Mordes, D., Frosch, M., Hyman, B., Lauffenburger, D., Haigis, K., 2015. “Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening,” Nature Scientific Reports, 5: 16622.

​

Wood, L.B., Winslow, A., Strasser, S., 2015. “Systems Biology of Neurodegenerative Diseases,” Integrative Biology, 7: 758-75.

 

Jun, H., Roy, J., Smith, T., Wood, L.B., Lane, K., Woolfenden, S., Punko, D., Bronson, R., Haigis, K., Breton, S., 2014. Charest, A., “ROS1 signaling regulated epithelial differentiation in the epididymis,” Endocrinology, 9: 3661-73

 

Cho, C., Hashimoto, T., Wong, E., Hori, Y., Wood, L.B., Zhao, L., Haigis, K., Hyman, T., Irimia, D., 2013. "Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation", Nature Scientific Reports, 3: 1823.

 

Kim, M., Kim, C., Wood, L.B., Neal, D., Kamm, R., and Asada, H., 2012. "Integrating focal adhesion dynamics, cytoskeleton remodeling, and actin motor activity for predicting cell migration on 3D curved surfaces of the extracellular matrix", Integrative Biology, 4: 1386-97.

 

Wood, L.B., Ge, R., Kamm, R., and Asada, H., 2012. "Nascent Vessel Elongation rate is Inversely Related to Diameter in In Vitro Angiogenesis", Integrative Biology, 4:1081-9.

 

Farahat, W.*, Wood, L.B.*, Zervantonakis, I., Ong, S., Schor, A., Kamm, R., and Asada, H., 2012. "Ensemble Analysis Of Angiogenic Growth In Three-Dimensional Microfluidic Cell Cultures", PLoS One, 7: e37333. doi:10.1371/journal.pone.0037333. *Equally contributing first and second authors.

 

Wood, L.B. and Asada H., 2011. "Cellular Stochastic Control of the Collective Output of a Class of Distributed Hysteretic Systems". Journal of Dynamic Systems, Measurement, and Control, 133: 061011.

 

Wood, L.B., Kamm, R., and Asada, H., 2011. "Stochastic Modeling and Identification of Emergent Behaviors of an Endothelial Cell Population in Angiogenic Pattern Formation", International Journal of Robotics Research, 30: 659-677.

 

Wood, L.B., Das, A., Kamm, R., and Asada, H., 2009. "A Stochastic Broadcast Feedback Approach to Regulating Cell Population Morphology for Microfluidic Angiogenesis Platforms", IEEE Transactions on Bio-Medical Engineering, 56: 2299-2303.

​

​

Full Length, Peer-Refereed Conference Papers

​

Wood, L. and Asada, H., 2011. An Experimentally Tuned Dynamic Model Predicting Cell Migration for Guidance of Sprouting Endothelial Cells, Proceedings of Dynamic Systems and Control Conference, Arlington, VA.

 

Wood, L., Kamm, R., and Asada, H., 2010. Time Lapse Observation Based Modeling and Identification of Cell Behaviors in Angiogenic Sprout Development. Proceedings of Dynamic Systems and Control Conference, Cambridge, MA.

 

Wood, L. and Asada, H., 2009. Stable Control of Distributed Hysteretic Systems Using Cellular Broadcast Stochastic Feedback. Proceedings of American Control Conference, St. Louis, MO 3519-3524.

 

Wood, L., Ueda, J., and Asada, H., 2008. Broadcast Feedback with Hysteresis Loop Control of Stochastically Behaving Cellular Units with Application to Cellular Shape Memory Alloy Actuators. Proceedings of Dynamic Systems and Control Conference, Ann Arbor, MI, 425-432.

 

Wood, L., Das, A., Kamm, R., and Asada, H., 2008 A Stochastic Control Framework for Regulating Collective Behaviors of an Angiogenesis Cell Population. Proceedings of IEEE Biomedical Robotics and Biomechatronics Conference, Scottsdale, AZ 390-396.

 

Wood, L., Das, and A., Asada, H., 2008. Broadcast Feedback Control of Cell Populations Using Stochastic Lyapunov Functions with Application to Angiogenesis Process Regulation. Proceedings of American Control Conference, Seattle, WA 2105-2111.

 

Wood, L. and Asada, H., 2007. Low Variance Adaptive Filter for Cancelling Motion Artifact in Wearable Photoplethysmogram Sensor Signals. Proceedings of IEEE Engineering in Medicine and Biology Conference, Lyon, France 652-655.

 

Wood, L. and Asada, H., 2006. Noise Cancellation Model Validation for Reduced Motion Artifact Wearable PPG Sensors Using MEMS Accelerometers. Proceedings of IEEE Engineering in Medicine and Biology Conference, New York, NY 3523-3528.

 

Wood, L. and Asada, H., 2005. Active Motion Artifact Reduction for Wearable Sensors Using Laguerre Expansion and Signal Separation. Proceedings of IEEE Engineering in Medicine and Biology Conference, Shanghai, China 3571-3574.